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Ritonavir or lopinavir/ritonavir tremendously raise plasma concentrations of oxycodone in balanced human volunteers as a consequence of inhibition of CYP3A4 and CYP2D6.[58] Rifampicin considerably reduces plasma concentrations of oxycodone due to robust induction of CYP3A4.Oxycodone is used for taking care of reasonable to serious acute or Persiste